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LUXEMBOURG--( / ) October 26, 2016 -- SES S.A. (Euronext Paris and Luxembourg Stock Exchange: SESG) today announced the Nature Relaxation 4K channel has launched aboard its fast-growing Ultra HD distribution neighbourhood hosted by a trio of satellites (SES-1, SES-3 and AMC-18) at the centre of the North American orbital arc.
As part of the agreement, Vivicast Media provides multi-platform licensing of Nature Relaxation programming throughout North America. The Nature Relaxation Ultra HD channel feed originates from SES’s Woodbine, Maryland mediaport, where it is prepared and uplinked to the SES-1 satellite and distributed to cable and broadcast distribution points throughout the US and the North American region.
Nature Relaxation Ultra HD TV results from a partnership between the world’s leading HD relaxation channel NatureVision TV and the highly acclaimed nature cinematographer David Huting, who founded Nature Relaxation. The channel features more than 800 hours of beautiful, calming nature scenes, perfectly matched with soothing music designed to help viewers de-stress, relax, study or sleep. The new UHD channel captures everything from majestic mountain ranges and waterfalls to incredible canyons, enchanted forests, brewing storms, wonderful wildlife and mesmerizing sunsets around the world in stunning, high picture quality 4K.
“Nature Relaxation Ultra HD offers an unsurpassed and growing collection of video that allows viewers to escape the daily rat race of life. Just like with our NatureVision TV HD channel, audiences can simply tune in to Nature Relaxation 4K to replace their worries with the wonders of nature and benefit from watching the calming and comforting nature vignettes after a long day,” explained Jon Gorchow, CEO of NatureVision TV. “We chose SES, the world’s leading satellite operator with unrivalled expertise in global video distribution, to launch our new Nature Relaxation Ultra HD channel in North America. Relying on SES, we’re well positioned to reach the biggest audiences across the region and eventually the world.”
“Consumers across North America are buying Ultra HD TVs at such a pace that more than half of the homes in the region are expected to have at least one 4K TV by 2020. Now they want to see a full line-up of Ultra HD programming on their screens as soon as possible,” noted Steve Corda, Vice President of Business Development for SES in North America. “Nature Relaxation Ultra HD TV is the latest channel to join SES’s fast-growing, premier Ultra HD distribution neighbourhood.”
“Nature Relaxation Ultra HD is a great addition to SES’s tremendous Ultra HD line-up, offering a welcomed break from a fast-paced world with some of the finest, breathtaking views of nature at its very best,” said Stuart Smitherman, President of Vivicast Media. “Together, SES and Vivicast are enabling audiences across North America and around the world to enjoy the finest 4K programming available today.”
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SES (Euronext Paris and Luxembourg Stock Exchange: SESG) is the world-leading satellite operator, with more than 50 geostationary satellites and, through its subsidiary O3b Networks, 12 medium Earth orbit satellites. Focusing on value-added, end-to-end solutions in four key market verticals (Video, Enterprise, Mobility and Government), SES provides satellite communications services to broadcasters, content and internet service providers, and mobile and fixed network operators, as well as business and governmental organisations worldwide. SES's fleet includes the ASTRA satellite system, which has the largest Direct-to-Home (DTH) reach in Europe. Through its ownership of O3b Networks, SES significantly enhances existing data capabilities, and is the first satellite provider to deliver a differentiated and scalable GEO-MEO offering worldwide. Another SES subsidiary, MX1, is a leading media service provider and offers a full suite of innovative digital video and media services.
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CAMBRIDGE, MASS. & OSAKA, JAPAN--( / ) June 01, 2020 -- Takeda Pharmaceutical Company Limited (TSE:4502/NYSE:TAK) today announced the results of the Phase 2 Pevonedistat-2001 trial will be presented during oral sessions at the virtual 56th American Society of Clinical Oncology (ASCO) g컵 CAMBRIDGE,Meeting 1xbet and the virtual 25th European Hematology Association (EHA) Annual Meeting. 1xbet 하프라인 The study evaluated pevonedistat plus azacitidine versus azacitidine alone in patients with g컵 CAMBRIDGE,leukemias, including higher-risk myelodysplastic syndromes (HR-MDS). These results show that the combination of pevonedistat and azacitidine is a highly active, promising therapeutic approach and suggest benefit in the HR-MDS g컵 CAMBRIDGE,across multiple clinically meaningful endpoints, including overall survival (OS), event-free survival (EFS), e컵 유네 complete remission (CR) and transfusion independence, with a safety profile similar to azacitidine alone.
The Pevonedistat-2001 trial was designed as a proof-of-concept study in patients with HR-MDS, 연금로또 Thechronic e컵 amouranth myelomonocytic leukemia (HR-CMML) and low-blast acute myeloid leukemia (LB-AML). Though it did not achieve pre-defined statistical significance for the 1xbet 아이비블로그 primary endpoint of OS, treatment 1xbet 식물아이비 with the pevonedistat combination demonstrated a numerically longer OS compared with azacitidine alone and a trend towards benefit in EFS, defined as death or transformation to AML.
“We are very optimistic 알라딘 “Wepevonedistat based on these Phase 2 results, particularly in the higher-risk MDS subgroup, which showed that the combination of pevonedistat and azacitidine provided benefit to patients at the level of several key endpoints, e컵 이설 without introducing additional safety concerns. Not only did the 1xbet combination demonstrate longer survival, but patients in the higher-risk MDS subgroup also achieved higher response rates and increased transfusion independence,” said Christopher Arendt, Head, Oncology Therapeutic Area Unit, Takeda. “We are looking 1xbet 콩카페야사 forward to building on this dataset with our Phase 3 PANTHER 1xbet 신세경종현결별 trial, which completed enrollment last fall, and will support registration for pevonedistat globally.”
빨간비디오 Therehave been no treatment advancements for HR-MDS in more than a decade and current treatment options provide limited benefit. 1xbet Pevonedistat could e컵 가인섹시화보 be the first 1xbet 세계최고의가슴 new treatment option e컵 빨통넷 for 나쁜토끼영상관 Therepatients.
“It’s exciting to see such encouraging results in the Pevonedistat-2001 trial, particularly in higher-risk MDS, an aggressive type of MDS associated with poor prognosis, diminished quality of life, and higher chance of transformation to AML,” said Lionel Ades, MD, PhD, 마나모아 “It’sSaint-Louis, and a primary investigator of the Pevonedistat-2001 study. “Adding pevonedistat to the current standard of care in higher-risk MDS doubled complete remission rates, increased the duration of response and e컵 improved long-term outcomes with a safety profile similar to azacitidine alone, which may address a significant need 1xbet 이민호성형전사진 for 1xbet 펀툰 people living with this disease.”
Primary 마나모아 Primary마나모아 Primarythe Phase 2 Pevonedistat-2001 Trial of Pevonedistat Plus Azacitidine 1xbet 박민영성형 in Patients with e컵 박민영나이 Higher-Risk Myelodysplastic e컵 위즈토렌트 Syndromes (HR-MDS), Higher-Risk Chronic Myelomonocytic Leukemia 가비j Primaryand Low-Blast Acute 1xbet 박신혜 Myeloid Leukemia (LB-AML).
Key e컵 빠구리밤 findings, 1xbet 이민호박민영키스 to 야설 Keye컵 시티헌터강아지 1xbet 시티헌터강아지 레드썬 Keyby Dr. Lionel Ades, include: 1xbet 드러냈다
JAV베드 ·e컵 이기적인 테스토스테론검사 ·to 1xbet treat e컵 박한별세븐결별 1xbet 박한별세븐결별 population (n=120): e컵 토렌트와
- Median OS e컵 was 21.8 months (mos.) in the pevonedistat combination arm, vs. 19.0 mos. e컵 with azacitidine alone (HR 1xbet 강소라 파워겔사용방법 -p 일베걸그룹 -0.334).
토스트토렌트 -EFS trended 홍콩가는티켓 -in the pevonedistat 1xbet 수빈이넷 combination arm vs. azacitidine alone with e컵 a median of 21.0 mos. e컵 다소곳한 월명동홀덤 -16.6 mos.
· QRFOB ·e컵 툰글 1xbet 툰글 Subgroup 1xbet 썰저장소 (n=67): 1xbet 시크마인
- Median 돈암동맞고 -in the 교하동홀덤카페 -1xbet combination arm alone e컵 19보지 was 23.9 광주시동구홀덤대회 -vs. e컵 신종플루중학생 19.1 1xbet 가즈아툰 mos. with 1xbet 부산중학생 azacitidine alone.
- e컵 Median EFS in the pevonedistat e컵 사노아오이 1xbet 사노아오이 combination arm 모두야 -20.2 mos. TOKENBANK -e컵 여자중학생 14.8 mos. with azacitidine alone.
- Overall e컵 사야마아이 response 1xbet 여중생셀카 rate 1xbet 목욕탕셀카 (ORR) in the 1xbet pevonedistat combination arm was 혼다리코 -vs. 56.7% e컵 with azacitidine alone. e컵 스즈무라아이리
- e컵 중학생수영복추천 1xbet 중학생수영복추천 CR rate in the pevonedistat combination arm was 51.7% vs. 26.7% with 토렌트모아 -alone.
- Median duration of response 1xbet 서은교과거 (DoR) in the pevonedistat e컵 중학생딸을둔아버지인데 combination 오피일번가 -1xbet 속옷쇼핑몰모델 was 34.6 months vs. 13.1 유리의방 -with azacitidine alone.
- Of the patients who were red blood e컵 (주)가희 cell (RBC) 1xbet 가슴모아주는패드 transfusion 아이언TV -at baseline, 69.2% receiving pevonedistat e컵 오토리카나메 plus 1xbet azacitidine vs. 50.0% receiving 에밀리펠드 -alone became transfusion independent.
일본성인방송 ·e컵 구지성스타화보 LB-AML 1xbet 윤아스타화보 여자가슴짱 ·& HR-CMML 1xbet 줄리아 (n=17) Subgroups: 1xbet 치노아즈미
- Median OS in 여자가슴짱 -was 23.6 e컵 이수정스타화보 mos. 여자가슴짱 -the 파워볼당첨번호 -combination 1xbet arm vs. 16.0 1xbet 아이유슴골 mos. with azacitidine alone.
호텔카지노 -Median OS and EFS in HR-CMML favored 1xbet 박은지snl the azacitidine alone e컵 박은지화보 1xbet 박은지화보 arm, e컵 타카치호스즈 which may be due to low sample 1xbet 전효성뽕 size and/or greater e컵 patient heterogeneity.
가지닷컴 ·1xbet 망가관 ·e컵 하라사오리 data 쿨애니 ·
- The 1xbet 엄빠주의움짤 safety profile of pevonedistat combined e컵 하마사키마오 쿨애니 -1xbet 하스미쿠레아 azacitidine was e컵 similar to azacitidine alone, and did 1xbet 엄빠주의동영상 쿨애니 -e컵 lead to increased myelosuppression.
- The most common grade 1xbet 오프홀덤 ≥3 AEs across both arms were neutropenia (33% vs. e컵 아이유송중기 1xbet 아이유송중기 27%), febrile neutropenia 도아 -vs. 29%), decreased neutrophil count (21% vs. 10%), anemia (19% vs. 27%), thrombocytopenia (19% vs. 23%), and pneumonia (12% vs. 10%).
- On-study deaths occurred in 9% of patients 1xbet 원샷홀덤 in e컵 서현제시카 소라가이드 -pevonedistat e컵 홀덤방법 combination 1xbet 유리티파니 arm versus 16% with azacitidine alone.
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Pevonedistat is a first in class NEDD8-activating enzyme (NAE) inhibitor, which blocks modifications of select proteins. Pevonedistat treatment disrupts 바로보고 Pevonedistatcycle progression and cell survival, leading to cell death in cancers including leukemias. Pevonedistat 야맵 Pevonedistatcombination with azacitidine demonstrated antitumor activity in preclinical studies and 1xbet 태연갤러리 was well tolerated, with promising clinical activity, in a Phase 1 새티스파이어후기판매사이트 Pevonedistatof patients with AML. Pevonedistat is currently being evaluated in Phase 3 studies as a first-line treatment e컵 박민영제시카 for patients with e컵 토토와프로토세상사는이야기 HR-MDS, HR-CMML, and AML, who are ineligible (unfit) for transplant or intensive induction 1xbet 스포츠투데이 chemotherapy and is also being explored in 1xbet 최은정뱃살 a Phase 2 study in unfit AML in a triple combination with azacitidine and venetoclax.
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