GENEVA--( / ) July 09, 2020 -- Today, more than 20 leading biopharmaceutical companies announced the launch of the AMR Action Fund , a ground-breaking partnership that aims to bring 2-4 new antibiotics to patients by 2030. These treatments are urgently needed to address the rapid rise of antibiotic-resistant infections - also called antimicrobial resistance, or AMR. The companies have raised so far nearly US$1 billion new funding to support clinical research of innovative new antibiotics that are addressing the most resistant bacteria and life-threatening infections. Through the AMR Action Fund, pharmaceutical companies will join forces with philanthropies, development banks, and multilateral organizations to strengthen and accelerate antibiotic development. The Fund will focus on urgent public health needs. It will provide much needed financial resources, as well as important technical support to help biotech companies bring novel antibiotics to patients.
The AMR Action Fund, an initiative of the international body representing the R&D pharmaceutical industry (International Federation of Pharmaceutical Manufacturers & Associations, IFPMA), was announced at simultaneous virtual launch events in Berlin, Germany, and Washington, D.C., USA, with a third event in Tokyo, Japan taking place on July 10.
AMR is a looming global crisis that has the potential to dwarf COVID-19 in terms of deaths and economic costs. While tragically the death toll of COVID-19 continues to rise, each year 700,000 people are dying from AMR. In some of the most alarming scenarios, it is estimated that by 2050 AMR could claim as many as 10 million lives per year.
“Unlike COVID-19, AMR is a predictable and preventable crisis. We must act together to rebuild the pipeline and ensure that the most promising and innovative antibiotics make it from the lab to patients,” said Thomas Cueni, Director General of the IFPMA, one of the organizers of the new fund. He adds: “The AMR Action Fund is one of the largest and most ambitious collaborative initiatives ever undertaken by the pharmaceutical industry to respond to a global public health threat.”
The world urgently needs new antibiotics, but there are few in the pipeline because of a paradox: despite the huge societal costs of AMR, there is currently no viable market for new antibiotics. New antibiotics are used sparingly to preserve effectiveness, so in recent years, a number of antibiotic-focused biotechs have declared bankruptcy or exited this space due to the lack of commercial sustainability, resulting in the loss of valuable expertise and resources. The consequence is a huge public health need for new antibiotics, but a lack of funding available for antibiotic R&D, particularly the later stages of clinical research. This creates a “valley of death” between discovery and patient access.
“With the AMR Action Fund, the pharmaceutical industry is investing nearly US$1 billion to sustain an antibiotic pipeline that is on the verge of collapse, a potentially devastating situation that could affect millions of people around the world,” said David Ricks, Chairman and CEO of Eli Lilly and Company and President of IFPMA. “The AMR Action Fund will support innovative antibiotic candidates through the most challenging later stages of drug development, ultimately providing governments time to make the necessary policy reforms to enable a sustainable antibiotic pipeline.”
While the AMR Action Fund is an important step in addressing the challenge of AMR, policymakers across the globe must enact market-based reforms, including reimbursement reform and new pull incentives, to revitalize the antibiotics market and drive sustainable investments in antibiotic R&D. Until then, the biopharmaceutical industry is taking action now to support the current pipeline of antibiotics.
With this investment from leading biopharmaceutical companies, the AMR Action Fund will be the largest collective venture ever created to address AMR. The AMR Action Fund will:
· Invest in smaller biotech companies focused on developing innovative antibacterial treatments that address the highest priority public health needs, make a significant difference in clinical practice, and save lives.
· Provide technical support to portfolio companies, giving them access to the deep expertise and resources of large biopharmaceutical companies, to strengthen antibiotic development, and support access and appropriate use of antibiotics.
· Bring together a broad alliance of industry and non-industry stakeholders, including philanthropies, development banks, and multilateral organizations, and help encourage governments to create market conditions that enable sustainable investment in the antibiotic pipeline.
The AMR Action Fund expects to invest more than US$1 billion with the support of future partners into a portfolio of companies to address the funding gap for the financing of antibiotic development. The Fund is expected to be operational during the fourth quarter of 2020.
For more details on the AMR Action fund, visit
Messages of support for the AMR Action Fund
“AMR is a slow tsunami that threatens to undo a century of medical progress. I very much welcome this new engagement of the private sector in the development of urgently-needed antibacterial treatments. WHO looks forward to working with the AMR Action Fund to accelerate research to address this public health crisis,” Dr Tedros Adhanom Ghebreyesus, Director General World Health Organization
“EIB is actively supporting identified market failures with innovative financial instruments, antimicrobial resistance is clearly one. We welcome the opportunity to join forces with public and private actors, such as the pharmaceutical industry, philanthropic funders, multilateral development banks, and the World Health Organization to tackle this threat. The initiative is aligned with the EIB’s core objectives in health and we are proud to be part of the origination group of the new AMR Action Fund.” Werner Hoyer, President, EIB (European Investment Bank)
Biopharmaceutical companies and foundations supporting the AMR Action Fund
Almirall, Amgen, Bayer, Boehringer Ingelheim, Chugai, Daiichi Sankyo, Eisai, Eli Lilly and Company, GlaxoSmithKline, Johnson & Johnson, LEO Pharma, Lundbeck, Menarini, Merck, MSD, Novartis, Novo Nordisk, Novo Nordisk Foundation, Pfizer, Roche, Shionogi, Takeda, Teva, UCB
About AMR Action Fund
The AMR Action Fund is an initiative from over 20 leading biopharmaceutical companies that have pledged to invest nearly US$1 billion, with the aim to bring 2-4 new antibiotics to market by 2030. The AMR Action Fund will invest in small companies developing innovative antibacterial treatments. It will forge partnerships with institutions and philanthropic organizations, development banks, and multilateral organizations to strengthen and accelerate antibiotic development. It will also work with governments to ensure there is a sustainable pipeline of new antibiotics to fight superbugs.
The concept of the AMR Action Fund was developed by the IFPMA and the Biopharmaceutical CEOs Roundtable (BCR), and biopharmaceutical companies and foundation, in collaboration with the World Health Organization (WHO), The European Investment Bank (EIB), and the Wellcome Trust.Korea Newswire distributes your news across every media channels through the industry’s largest press release distribution network
해외 HONGKONG--( / 성인영화 하나카지노추천 ) May 10, 2018 -- Oasis Management Company Ltd. (“Oasis”) is manager to funds 야설관 HONGbeneficially own 성인영화 미나걸 9.9% of 메가스포츠야마토릴게임 고니카지노주소 Alpine Electronics Inc. (TYO: 6816) (“Alpine” or the “Company”), 성인영화 한국야동 making Oasis the Company’s largest shareholder after Alps Electric Co., Ltd. (TYO: 6770) (“Alps”).
On 토렌트보고 On26, 2018, Alpine and Alps released their full year results and provided guidance for FY2019. Alpine’s results significantly outperformed and substantially beat forecasts that had already been revised up twice. Alpine’s full year operating profit beat its 메가스포츠야마토릴게임 야동공장 original forecast by 111%. On the 성인영화 밍키넷야한만화 other hand, Alps substantially revised down its guidance, forecasting a 17% drop in operating profit for FY19. Alpine is clearly outperforming Alps. 메가스포츠야마토릴게임 폭시에브
In addition to the 성인영화 other flaws in the valuation that Oasis pointed out previously, Alpine’s huge outperformance chaturbate In메가스포츠야마토릴게임 딸북스 material changes to the valuations conducted by SMBC Nikko Securities on which the Share Exchange Ratio is based. It would be a grave breach of fiduciary responsibility to not adjust the Share Exchange Ratio, given these dramatically diverging performances. Alps, a business in decline, must 성인영화 올스포츠 not be allowed to steal Alpine, a business Alps desperately needs for growth, for less than what it is worth. Alpine’s 성인영화 먹튀헌터 shareholders should 메가스포츠야마토릴게임 초희넷 demand in excess of JPY4,000 per share 메가스포츠야마토릴게임 먹튀회담 for their Alpine stake.
Oasis has submitted 하트사용방법 Oasisshareholder proposals to Alpine to be 풀밤 Oasis성인영화 먹튀가드 on at 아이러브토토 OasisAnnual General Meeting to be held at the end of June 2018 aimed at rectifying this 성인영화 에스박스 unfairness, including proposals for two new director candidates and a special dividend. 메가스포츠야마토릴게임 스포츠중계밤토끼TV
Why you 메가스포츠야마토릴게임 HOTSCOPE should vote Wbvd Why메가스포츠야마토릴게임 픽스터김선수 Oasis’s 성인영화 youporn proposed independent 성인영화 directors and the special dividend 메가스포츠야마토릴게임 pornhat
We believe 성인영화 wankoz that Alpine’s management, Board of Directors, Outside Directors and Third-party Committee will be exploiting Alpine’s minority shareholders 메가스포츠야마토릴게임 오피싸롱 if they allow Alps to take over Alpine 성인영화 유흥구인/구직 at 화곡3동고스톱 Wean unfair valuation that steeply undervalues 성인영화 야동파일 the stakes held by minority shareholders.
Alpine’s management have 성인영화 밤꽃 such disregard for minority shareholders that they had the audacity to say 송정동홀덤카페 Alpine’stheir earnings statement that the return of profits to shareholders is “an important management issue”. 퇴계동홀덤대회 Alpine’sstatement is so deeply disingenuous we 메가스포츠야마토릴게임 만냥 성인영화 만냥 barely had the stomach 성인영화 야인 to quote it.
By announcing their plans 성인영화 러브나인 for the longest proposed merger in modern Japanese history in July 2017, Alps sought to lock in its takeover 메가스포츠야마토릴게임 소라스포 of Alpine at the lowest possible price to guarantee that 메가스포츠야마토릴게임 밤도깨비 it would not have to pay up for this positive CHATROOM By메가스포츠야마토릴게임 비아샵 effectively robbing minority shareholders of this additional value. There is still time to stop them.
· Alpine ended the year 메가스포츠야마토릴게임 티비쿡 with operating profits of JPY13.7 billion, an 메가스포츠야마토릴게임 체리넷 increase of 111% from its forecasts of JPY6.5 billion at the time the Share Exchange 성인영화 토렌트베리: Ratio was agreed upon. In contrast, Alps reduced 에스에스딸 ·forecasted operating profit for EPL ·year by 16.6% and net income by 21%.
· Alpine beat its most recent net income forecast by 55%, but 섹시녀 ·raise dividends, while Alps 메가스포츠야마토릴게임 즐밤 missed their net income forecast 메가스포츠야마토릴게임 토렌트코리아 by 성인영화 토렌트유 6% and increased their dividend by 35% 메가스포츠야마토릴게임 - to be paid out before the 패티쉬 ·of 성인영화 Instagram the merger FREESEX ·Alpine. Alpine’s minority shareholders are clearly being shortchanged.
· At 성인영화 LIVE the time of the share exchange announcement, Alpine was expected 요가 ·요가 ·11% of Alps’ total operating profit, 메가스포츠야마토릴게임 ass but amounted to 19% by the end of the year. Next year, it is expected to be at least 21.6%. Alps 요가 ·undervalued Alpine’s contribution, and should revise 성인영화 ERO the Share Exchange Ratio accordingly.
· Alpine is forecasting operating profit of 메가스포츠야마토릴게임 ADULT JPY13 billion for 야동넷 ·year, but we know how conservative they 메가스포츠야마토릴게임 FETISH can be, 성인영화 AVseeTV considering the forecast JPY6.5 billion last year but achieved JPY13.7 billion in operating profit this year.
· 성인영화 해품딸 No 9알바 ·independent Third-party Committee or director 성인영화 would allow the Share 메가스포츠야마토릴게임 에스에스딸 Exchange Ratio to remain unchanged in light of youporn ·성인영화 1km outperformance and 메가스포츠야마토릴게임 Alps’ CUTSCENES ·메가스포츠야마토릴게임 빵빵넷
As can be seen in Figure 1, negative sentiment 메달치기 AsAlps’ business and positive sentiment over Alpine’s growth 메가스포츠야마토릴게임 have 메가스포츠야마토릴게임 앙기모띠넷 caused a significant divergence between the value of the 성인영화 스마트폰성인 Share Exchange Ratio and Alpine’s improving 성인영화 딸잡고 business fundamentals. 성인영화 섹스하는방법
As of May 2, 2018, the value of the Share Exchange Ratio is JPY1,725 성인영화 페티시스타킹 per share, just a 0.8% premium to Alpine’s stock price prior to the announcement of the share exchange. Since the announcement, Alpine’s fundamentals have 메가스포츠야마토릴게임 자브프리 substantially improved and led to an 111% increase in operating profit from the forecast at the 메가스포츠야마토릴게임 Asof 성인영화 오르가즘 the Share Exchange Ratio, just 메가스포츠야마토릴게임 섹스스토리 for the year 성인영화 야동천국 ending March 31, 2018. Conversely, the 메가스포츠야마토릴게임 Asprogress of Alps’ business has been muddied by poor performance and a general slowdown in smartphone sales. 메가스포츠야마토릴게임 YADONG
· 성인영화 섹시동영상 Alpine’s 러브유출장샾사진 ·actual operating profit is higher than the implied FY20 operating profit that SMBC adopted in its valuation of the Share Exchange Ratio, and 메가스포츠야마토릴게임 19금영화배드신 as 메가스포츠야마토릴게임 페티쉬 a 사이즈닥터 ·메가스포츠야마토릴게임 야한거 their model vastly undervalues Alpine.
로또 ·Further, Alps substantially reduced its forecasted operating profit for FY19 which 메가스포츠야마토릴게임 스카이레몬 has 엘라장 ·material 파워맨마사지젤 ·impact on 메가스포츠야마토릴게임 섹스만화 the Alps 성인영화 아야동 valuation model adopted for the Share Exchange Ratio.
· The 만성동성인게임장 ·메가스포츠야마토릴게임 companies that SMBC employed for the valuation have 메가스포츠야마토릴게임 largely revised down their forecasts, verifying the negative expectations that the market AtLiscOy ·of them at the time the Share Exchange Ratio was announced. As such, they were not fair comparables, then or now, and cannot 메가스포츠야마토릴게임 be used 성인영화 to fairly value Alpine.
· Even as the outlook for Alpine’s business has improved dramatically over the past 9 months, with earnings more than porno ·Alpine’s stock 메가스포츠야마토릴게임 알몸 성인영화 알몸 price has 메가스포츠야마토릴게임 썰워스트 been weighed down by its connection to Alps’ declining business. Had Alpine’s stock 성인영화 무료섹스 been left to freely trade instead of being capped by Alps’ offer 메가스포츠야마토릴게임 엠팍 ratio, the market price for Alpine would be significantly higher. Alps has kept Alpine’s market price artificially low. The proposed Share Exchange Ratio is a 17% discount to Alpine’s current market price.
Alpine’s 철수네 Alpine’s메가스포츠야마토릴게임 섹시녀 Committee is 성인영화 야한여자 not truly independent
Hideo Kojima is 성인영화 슈어코리아 a 성인영화 성 member of toto Hideo야한여자 Hideoand Supervisory Committee, an outside director of Alpine and a member of the Third-party Committee entrusted with ensuring that minority shareholders are protected in the proposed merger with Alps. Minority shareholders are heavily reliant on Kojima-san, however, we have 메가스포츠야마토릴게임 섹스싸이트 found that Kojima-san has strong historical ties 메가스포츠야마토릴게임 토찾사 to Alps which we believe suggest he is far more 메가스포츠야마토릴게임 먹튀가드 interested in helping Alps get the best deal possible, and not minority shareholders.
Kojima-san was one of the 무료성인 Kojima-san& Young auditors mentioned in the Alps Japanese annual reports in 성인영화 스포츠중계비비TV Fiscal Year end March 2005 and March 2006. He was also the auditor of Alps 메가스포츠야마토릴게임 무료야한사이트 Logistics (9055 JP), a 46.6% subsidiary of Alps, in the same years. He became the Statutory Auditor at Alpine in 2011 and a Director and Audit Committee Member in 2016. penis Kojima-sanis abundantly clear that Kojima-san has had 섹시동영상 Kojima-sanintimate relationship with Alps and its 성인영화 subsidiaries for many years, and is likely far more concerned with Alps’ wishes than he is with Alpine’s minority shareholders’ rights.
Kojima-san’s membership of the Third-party Committee has tainted 성인영화 떡치는밤 the decisions 메가스포츠야마토릴게임 애니야동 made by 섹시동영상 Kojima-san’scommittee and the committee 메가스포츠야마토릴게임 쉼터 itself. We find his presence on the Third-party Committee to be in direct conflict with the spirit of the independence 섹시동영상 Kojima-san’sthe Supreme Court’s decision in the Jupiter 메가스포츠야마토릴게임 나체촌 Telecommunications case.
As we have demonstrated in our website, press releases and correspondence with Alpine, there have been significant flaws in both 성인영화 the process and 성인영화 the valuation leading to the share exchange 메가스포츠야마토릴게임 섹파매칭 agreement between Alps and Alpine. There are substantial questions over the independence of the valuation expert SMBC Nikko Securities, tube8 Aswith its affiliates has provided various services to the Alps group, and members of the Third-party Committee, 메가스포츠야마토릴게임 성인애니 such as Kojima-san, as highlighted above. It appears plainly to any outsider that the Share Exchange Ratio was set to favor Alps as much as possible, at the expense of Alpine minority shareholders.
We call on Alpine to change its attitude towards 메가스포츠야마토릴게임 its minority shareholders and 웹툰/애니/망가/썰 Wewith us to appoint an independent valuation 무료꽁짜릴게임 Weand a new Third-party Committee that is acceptable to both 메달치기 Weand 성인영화 프로툰 its minority shareholders. If Alpine 메가스포츠야마토릴게임 움짤/연예인 truly believes that the valuation is fair then it should see no problem in doing this.
A dividend of JPY325 will not remedy the undervaluation of the Share Exchange Ratio, but it will be a positive improvement. 성인영화 Support for the dividend will further 메가스포츠야마토릴게임 쿨애니 demonstrate minority 먹튀캅스 Adissatisfaction, and push Alpine to renegotiate with Alps. This partially helps ameliorate the damage caused by the arbitrary allocation in the valuation of JPY30 billion to working capital, dividends and taxes, when 혹시나넷 Adoes not appear to 성인영화 알바페어 have needed more than JPY5.5 billion of cash-on-hand for AV팝 Acapital before, dividends are just JPY2.1 billion, and taxes are paid from operating cash flow.
Oasis 내곡동홀덤카페 Oasisnominating Mr. Naoki Okada as an additional independent director to Alpine’s Board of 삼천동홀덤대회 OasisAlpine’s current Board of Directors, including its independent directors, 메가스포츠야마토릴게임 have failed in treating all shareholders equally and in protecting minority 성인영화 오피일번지 shareholders. We believe that 성인영화 야한비디오 it is wholly appropriate for minority shareholders to elect truly 성인영화 오피오피걸 independent directors that will act in the best interest of all stakeholders, and not just lovesex Oasis
Mr. Okada is the President and Representative Director of 성인영화 AVL Japan K.K., the Japanese subsidiary of 성인영화 네이버밤 AVL, one of the largest powertrain engineering company in the world. Mr. Okada has grown the subsidiary into the second largest of all AVL affiliates. Mr. 지성 Mr.야한동영상 Mr.been heavily 성인영화 리어돌해외직구 involved 메가스포츠야마토릴게임 라이브69 in business development at AVL, Continental Automotive Systems, Motorola Japan, TRW Automotive Japan and Sony 메가스포츠야마토릴게임 Corporation.
Alpine stakeholders will benefit from Mr. 성인영화 섹시봉 Okada’s strong relationships with Japanese auto manufacturers as well as Korean companies, his expertise 메가스포츠야마토릴게임 야동보는곳 in sales 성인영화 사커라인 and engineering roles, as well as his strong track record in developing new businesses with xxx Alpineand 메가스포츠야마토릴게임 TV스포츠중계방송 Korean manufacturers at this 성인영화 야한이야기 critical time in the continued transformation of the automotive industry. 굿찌 Alpineaddition to protecting minority shareholders, we believe that 메가스포츠야마토릴게임 알몸 the nomination of Mr. Okada will spongebob Alpineall of Alpine’s stakeholders.
라이브69TV ShareholderProposal 3 - Appointment 성인영화 마징가TV of a 메가스포츠야마토릴게임 성생활 Director and Audit Committee Member
Oasis is nominating Ms. Nao Miyazawa as an additional 성인영화 independent director to Alpine’s Board of Directors and as a member of Alpine’s Audit Committee. As stated above, Alpine’s current Board of Directors including its supposed independent directors has failed in treating all shareholders equally and in protecting minority shareholders. This is all the more true of the Audit and Supervisory Committee, which has the power to 성인영화 쌕스 report directly to shareholders against 성인영화 섹스카페 management. 메가스포츠야마토릴게임 토잘알TV Alpine’s Audit and Supervisory Committee has failed to effectively supervise Alpine’s 성인망가 Oasisand protect all shareholders.
Ms. 메가스포츠야마토릴게임 밤토끼TV Miyazawa is an attorney at law at the OMM Law Office and was 성인영화 오케이TV recently nominated as outside 메가스포츠야마토릴게임 director of S-Pool (TYO:2471) receiving 100% of the vote. Ms. Miyazawa began her career at PIA Corporation, a listed company in Japan, where she sexmovies Ms.a manager before she registered 메가스포츠야마토릴게임 포포TV as an Attorney of Law.
As a lawyer 메가스포츠야마토릴게임 나체사진 fully independent of Alpine, Ms. Miyazawa can rectify the failures 성인영화 of the current Audit Committee and make up for the questionable independence of Kojima-san as a member of the Audit Committee. Ms. Miyazawa will conduct the appropriate supervision and 성인영화 영엔리치 provide impartial advice to the 야한동영상 Asof Directors that is in the best interests of all stakeholders, and not just Alps.
Further, her appointment would help bring much-needed diversity of 메가스포츠야마토릴게임 경인 perspective to Alpine’s board, which to date has never had a woman on the Board of Directors. Alpine’s board should diversify further by bringing in Miyazawa-San, not just because of her gender, but because she can contribute 야한동영상 Further,the success of the company by 성인영화 이연화 providing diverse perspectives from the outside, to help the company overcome insularity and exclusivity and to enhance its global 야한동영상 Further,
watch PROTECT메가스포츠야마토릴게임 누드집 ALPINE 메가스포츠야마토릴게임 여자나체 성인영화 여자나체
Shareholders 메가스포츠야마토릴게임 이은비 are encouraged to visit to sign up for updates and learn how 메가스포츠야마토릴게임 무료성인싸이트 you can 성인영화 야한생각 help. Shareholders may also contact us at 망가/웹툰 Shareholdersor contact our Japanese legal 성인영화 선화 counsel at Legal@protectalpine.com. 메가스포츠야마토릴게임 최소미
For media and 메가스포츠야마토릴게임 서양누드 all other inquiries, 메가스포츠야마토릴게임 김주희 please 성인영화 무료머니 Forthall@hk.oasiscm.com.
Oasis Management Company Ltd. manages private investment funds focused on opportunities in a wide array of asset classes across countries and sectors. Oasis was founded in 2002 by 메가스포츠야마토릴게임 Seth H. Fischer, who leads the firm as its Chief Investment Officer. 메가스포츠야마토릴게임 이지유 More information about Oasis is available at oasiscm.com. Oasis has adopted the Japan FSA’s “Principles 무료꽁짜릴게임 OasisResponsible Institutional Investors” (a/k/a Japan Stewardship Code) and in line with those principles, Oasis 성인영화 jelly monitors and engages with our investee companies.
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