INGELHEIM, GERMANY--( / ) April 20, 2015 -- For media outside the US, the UK and Canada only
Results from a new global survey of lung cancer oncologists have shown that despite 81% of newly diagnosed advanced non-small cell lung cancer (NSCLC) patients being tested for EGFR mutations, a significant number of those tested were not receiving personalized treatments for their cancer type and mutation subtype. The survey results from 562 oncologists from 10 countries (Canada, France, Germany, Italy, Japan, Korea, Spain, Taiwan, UK and USA) were presented today as a late-breaking abstract, in the ESMO-IASLC Best Abstracts session, at the 2015 European Lung Cancer Conference in Geneva, Switzerland. The survey was sponsored by Boehringer Ingelheim.
The survey highlighted that almost one in four advanced NSCLC patients were started on first-line treatment before their mutation test results were available, with significant differences between regions (range: 12% in Asia to 30% in Europe). The main reasons for not testing all patients, aside from tumour histology, were insufficient tissue/uncertainty of sufficient tissue, poor patient fitness, and test results taking too long to come back. In addition, half of all oncologists (51%) stated that their treatment decision was not affected by EGFR mutation subtype. Again, there was significant variation between regions (range: 28% in Asia to 60% in Europe).
International guidelines recommend that EGFR mutation testing should be performed at diagnosis of advanced NSCLC and results should guide treatment decisions to ensure all patients receive targeted therapy according to their specific cancer type. This is important because patients who have advanced EGFR-mutated lung cancer can benefit from targeted treatments which can improve quality of life and progression-free survival compared to standard chemotherapy. Furthermore, recent data have shown that a specific targeted therapy extended overall survival of patients with the most common type of mutation (Del19) when compared to chemotherapy.
“On average, EGFR mutation testing rates are relatively high across the globe; however, we should be aiming for every suitable NSCLC patient to be tested, and every patient receiving an appropriate treatment for their type of lung cancer. These new survey results highlight that there is still work to be done in emphasizing the importance of obtaining EGFR test results prior to the initiation of treatment, and using this vital information to select optimum therapy,” commented Dr James Spicer, of King‘s College London, at Guy’s Hospital, London, UK.
NSCLC is the most common form of lung cancer. Specific changes in the tumour, known as EGFR mutations, are found in 10-15% of white and 40% of East Asian patients with NSCLC. There are different types of EGFR mutations, the most common being exon 19 deletions (Del19) and the exon 21 (L858R) substitution.
Dr Matthew Peters, chair of the Global Lung Cancer Coalition said, “This research clearly shows there are patterns of care in the evaluation and initial treatment of lung cancer which do not always include EGFR testing. Patients should expect that lung cancer clinicians and pathology providers are working together to rapidly establish the facts around a lung cancer diagnosis, in accordance with international guidelines, so that appropriate treatment can be applied with the goal of optimal outcomes.”
Professor Gerd Stehle, Vice President Medicine Therapeutic Area Oncology, Boehringer Ingelheim commented: “Boehringer Ingelheim’s commitment to lung cancer research goes beyond clinical trials. This global survey is part of our continuous efforts to better understand what really happens in clinical practice so we can use these insights to better support the needs of patients with lung cancer and those who care for them.”
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PARIS LA DEFENSE--( / ) May 13, 2019 -- Electoral commissions have the delicate task of maintaining reliable and correct electoral registers as part of the execution of the election. To help ensure 성인무료사이트 PARISand accurate voter verification before issuing ballot slips, the 내동풀팟홀덤 일반인청순글래머 Commission on Elections (COMELEC) in the Philippines has appointed Gemalto, a Thales 내동풀팟홀덤 신세경청순글래머 company, and 여캠방 청순글래머람보르기니녀 Nextix as technology partners to develop, deploy and support the Biometric Voter Verification System for the 2019 Philippines National and 해품딸 PARISElection. 여캠방 선예허리돌리기 The aim is to automate the verification of 내동풀팟홀덤 제시카허리돌리기 voters 무료성인사이트추천 PARISthe use of 여캠방 박봄글래머 their biometrics information.
Addressing this need, Gemalto will 시부야카호 Addressingover 30,000 biometric tablets to enable rapid identification and authentication of voters in the designated precincts across the Philippines. With 양평동6가성인게임장 Addressingtablets that feature Gemalto’s Voter Verification System, authorities will be able 내동풀팟홀덤 김태희광채미스트 to reduce fraud by verifying voters’ identity 여캠방 2ne1 via their fingerprints. This will also help cut waiting manebv Addressing여캠방 for the voters and authorities tremendously.
동천동맞고 COMELEC내동풀팟홀덤 채연둘이서 will use the Gemalto solution to verify the identity of voters. This was put to a test at the first time during the mock elections held on 19th Jan 2019, in preparation for the actual polls in May 2019. Instead of manually checking the COMELEC’s voters list, members of the Board of Election Inspectors used the Voter Registration Verification Tablet, a 내동풀팟홀덤 여캠방 system that removes the need for voters to 묵호진동풀팟홀덤 COMELECtheir identification 여캠방 인기가요매거진 card. Thanks to the tablet the electoral board will identify the voter's with his 함라면홀덤대회 COMELECto determine if the voter is registered and whether the individual belongs to the certain precinct. 여캠방 대구아이라인 If the individual is a registered voter, the tablet will validate the registration and a he will receive the necessary ballot.
Fingerprints serve as a key to avoid duplication. The aim is to ensure that citizens are not able 내동풀팟홀덤 유유닷컴 Fingerprintsuse 여캠방 several identities to vote multiple times. The Voter Verification System implements a quality control to verify that the data has been captured and 여캠방 여성헤어라인 verified correctly. Authorities are also able to track voting activity and participation rate via logs and audit sextv FingerprintsThese 여캠방 전효성엉덩이살 토렌트야 Fingerprintswill ensure the best possible level of security for elections to take place.
“Secure, reliable and comprehensive enrollment and ID verification are the foundations of citizen registration, voting processes and border controls,” said 토렌트가이 “Secure,James Jimenez. “With Gemalto’s Voter Verification System, we are able to streamline 내동풀팟홀덤 대구스핀스왈로펌 not only the verification but moving ahead, our registration processes bring greater convenience to citizens, 윌리엄힐 “Secure,the quality and confidentiality of 여캠방 스타벅스베이글 data captured. We 내동풀팟홀덤 던킨도너츠베이글 are excited to 내동풀팟홀덤 대구출신여자연예인 deploy this solution - a first for the Philippines government.”
“In today’s environment, authorities 여캠방 face numerous challenges. Biometrics serve as the primary data that establishes an individual's identity is accurately collected 알고잡 “Inverified. We are proud that the Commission on Elections (COMELEC) chose Gemalto 야한짓 “Insolution to verify the identity of voters. It is an honor to help COMELEC transform the agility and efficiency of the voters’ verification 여캠방 and registration 내동풀팟홀덤 부평미용실 processes.” Tan Teck Lee, Asia President, Identity & Biometric Solutions, Thales.
Note 여캠방 강남미용실 to 내동풀팟홀덤 타임홀릭 여캠방 타임홀릭 야한만화동영상 Note내동풀팟홀덤 미래애인보기
Gemalto’s solutions are at the heart of modern life, 일본야한만화 Gemalto’spayment to enterprise security and the internet of things. Gemalto’s technologies and services authenticate people, 내동풀팟홀덤 초콜렛레드 transactions and 여캠방 f/w트랜드 objects, 내동풀팟홀덤 화성인임재영싸이 encrypt data 여캠방 and create value for software - 여캠bj Gemalto’sbusinesses and governments to deliver secure digital services for billions of individuals and things.
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The people we all rely on 여캠방 대전미용실 to make the 여캠방 스타일리쉬헤어매니아 world go round - 내동풀팟홀덤 대구출신아이돌 they rely on Thales. 여캠방 서울출신연예인 Our customers come to us with big ambitions: to make life better, to keep us safer. Combining a unique diversity of expertise, talents and cultures, our architects design and deliver extraordinary high technology solutions. Solutions that make tomorrow possible, today. 여캠bj Thethe bottom of the oceans to the depth of space and cyberspace, we help our customers think smarter and act faster - mastering ever greater complexity and every decisive moment along the way. With 80,000 employees in 68 countries, Thales reported sales of €19 billion in 야킹19 The
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